ELL Antikörper (AA 531-620) (Cy5)

Produktnummer ABIN1417362

Produktdetails anti-ELL Antikörper (Cy5)

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Bindungsspezifität: AA 531-620

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELL Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ELL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Andere Bezeichnung: ELL (ELL Produkte)

Synonyme: wu:fc60b11 antikoerper, zgc:63836 antikoerper, C19orf17 antikoerper, ELL1 antikoerper, MEN antikoerper, PPP1R68 antikoerper, Ell1 antikoerper, Men antikoerper, elongation factor for RNA polymerase II antikoerper, elongation factor RNA polymerase II antikoerper, ELL antikoerper, ell antikoerper, Ell antikoerper

Hintergrund:

Synonyms: ELL_HUMAN, Eleven nineteen lysine rich leukemia gene, Eleven-nineteen lysine-rich leukemia protein, ELL1, elongation factor RNA polymerase II, Men, RNA polymerase II elongation factor, RNA polymerase II elongation factor ELL.

Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.

Gen-ID: 8178