ELL Antikörper (Internal Region)

Produktnummer ABIN6257163

Produktdetails anti-ELL Antikörper

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ELL Antibody detects endogenous levels of total ELL.

Homologie: Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ELL, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Andere Bezeichnung: ELL (ELL Produkte)

Synonyme: wu:fc60b11 antikoerper, zgc:63836 antikoerper, C19orf17 antikoerper, ELL1 antikoerper, MEN antikoerper, PPP1R68 antikoerper, Ell1 antikoerper, Men antikoerper, elongation factor for RNA polymerase II antikoerper, elongation factor RNA polymerase II antikoerper, ELL antikoerper, ell antikoerper, Ell antikoerper

Hintergrund:

Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Gene: ELL

Molekulargewicht: 65 kDa

Gen-ID: 8178

UniProt: P55199