ELL Antikörper

Produktnummer ABIN7183500

Produktdetails anti-ELL Antikörper

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human ELL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Andere Bezeichnung: ELL (ELL Produkte)

Synonyme: wu:fc60b11 antikoerper, zgc:63836 antikoerper, C19orf17 antikoerper, ELL1 antikoerper, MEN antikoerper, PPP1R68 antikoerper, Ell1 antikoerper, Men antikoerper, elongation factor for RNA polymerase II antikoerper, elongation factor RNA polymerase II antikoerper, ELL antikoerper, ell antikoerper, Ell antikoerper

Hintergrund:

Background: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).
Simone F., Blood 98:201-209(2001).
Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005).

Aliases: ELL antibody, C19orf17RNA polymerase II elongation factor ELL antibody, Eleven-nineteen lysine-rich leukemia protein antibody

UniProt: P55199