RIMS3 Antikörper (AA 21-120) (Cy5.5)

Produktnummer ABIN1408697

Der Kaninchen Polyklonal Anti-RIMS3-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, RIMS3 in Proben von Human zu detektieren.

Kurzübersicht für RIMS3 Antikörper (AA 21-120) (Cy5.5) (ABIN1408697)

Target: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIMS3 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RIMS3 Antikörper (Cy5.5)

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RIMS3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RIMS3

Target: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Andere Bezeichnung: RIMS3

Hintergrund:

Synonyms: NIM 3, NIM3, Rab 3 interacting molecule 3, Regulating synaptic membrane exocytosis 3, Regulating synaptic membrane exocytosis protein 3, RIMS 3, RIMS-3, RIM 3, RIM3, RIM3 gamma, RIMS3, RIMS3_HUMAN.

Background: Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.

Gen-ID: 9783

Pathways: Stem Cell Maintenance, Synaptic Vesicle Exocytosis