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PKC epsilon Antikörper (pSer729) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKC epsilon in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN1399999

Kurzübersicht für PKC epsilon Antikörper (pSer729) (Biotin) (ABIN1399999)

Target

Alle PKC epsilon (PRKCE) Antikörper anzeigen
PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Reaktivität

  • 93
  • 53
  • 45
  • 6
  • 4
  • 1
  • 1
Maus

Wirt

  • 100
  • 25
  • 1
Kaninchen

Klonalität

  • 94
  • 32
Polyklonal

Konjugat

  • 71
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser PKC epsilon Antikörper ist konjugiert mit Biotin

Applikation

  • 110
  • 50
  • 38
  • 29
  • 28
  • 27
  • 27
  • 12
  • 12
  • 7
  • 7
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 18
    • 15
    • 12
    • 10
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer729

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human PKCE around the phosphorylation site of Ser729

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

    Andere Bezeichnung

    PKC Epsilon

    Hintergrund

    Synonyms: PKC epsilon phospho S729, PKC Epsilon phospho Ser729, p-PKC Epsilon Ser729, PKC-A, PKC alpha, AAG6, Aging associated gene 6, PICK 1, PKC A, PKCA, PKC A, PRKCA, Protein Kinase C alpha, Protein kinase C alpha type, KPCE_HUMAN.

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008].

    Gen-ID

    5581

    UniProt

    Q02156

    Pathways

    T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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