STIM1 Antikörper (AA 85-180) (Biotin)
Kurzübersicht für STIM1 Antikörper (AA 85-180) (Biotin) (ABIN1399561)
Target
Alle STIM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 85-180
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Spezifität
- May cross react with STIM2
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Kreuzreaktivität
- Ratte
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Homologie
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human STIM1
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Isotyp
- IgG
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Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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Andere Bezeichnung
- STIM1
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Hintergrund
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Synonyms: GOK, TAM, TAM1, IMD10, STRMK, D11S4896E, Stromal interaction molecule 1, STIM1
Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
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Gen-ID
- 6786
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UniProt
- Q13586
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Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
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