POLB Antikörper (AA 55-160) (Biotin)
Kurzübersicht für POLB Antikörper (AA 55-160) (Biotin) (ABIN1399555)
Target
Alle POLB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 55-160
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DNA Polymerase beta
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- POLB (Polymerase (DNA Directed), beta (POLB))
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Andere Bezeichnung
- DNA Polymerase beta
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Hintergrund
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Synonyms: DNA polymerase beta, POLB
Background: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
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Gen-ID
- 5423
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UniProt
- P06746
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Pathways
- DNA Reparatur
Target
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