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c-MYC Antikörper (pThr373) (AbBy Fluor® 350)

MYC Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal AbBy Fluor® 350

Produktnummer ABIN1399113

Datenblatt (PDF)

Target Alle c-MYC (MYC) Antikörper anzeigen

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
Bindungsspezifität
59

48

44

41

24

22

17

15

14

13

10

7

7

6

6

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr373
Reaktivität
359

161

114

15

15

13

13

13

9

9

9

6

6

6

5

4

3

3

2

2

1

1

1

1

1

1

1
Human, Maus
Wirt
276

101

7

5

3

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
271

122
Polyklonal
Konjugat
193

31

24

23

8

8

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser c-MYC Antikörper ist konjugiert mit AbBy Fluor® 350
Applikation
287

140

97

81

75

58

55

28

26

24

18

14

12

11

7

4

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität

Human, Maus

Homologie

Rat,Cow,Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human C-Myc around the phosphorylation site of Ser373

Isotyp

IgG

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Applikationshinweise

FCM 1:20-100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Andere Bezeichnung

C-Myc (MYC Produkte)

Hintergrund

Synonyms: MycSer373, MycS373, p-MycSer373, p-MycS373, AU016757, Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, Cellular myelocytomatosis oncogene,
Background: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

Gen-ID

4609

Pathways

p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt