UBE2D1 Antikörper (AA 81-147) (AbBy Fluor® 488)

Produktnummer ABIN1398604

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UBE2D1 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UBE2D1 Antikörper (AA 81-147) (AbBy Fluor® 488) (ABIN1398604)

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-UBE2D1 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 81-147

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2D1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2D1

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Andere Bezeichnung: UBE2D1

Hintergrund:

Synonyms: E217KB1, SFT, Stimulator of Fe transport, UB2D1_HUMAN, UBC 4/5, UBC4/5, UBC4/5 homolog, UBCH 5, UBCH 5A, UBCH5, UBCH5A, Ube2d1, Ubiquitin carrier protein, Ubiquitin carrier protein D1, Ubiquitin conjugating enzyme E2 17 kDa 1, Ubiquitin conjugating enzyme E2 D1, Ubiquitin conjugating enzyme E2D 1 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2D 1, Ubiquitin protein ligase D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E217KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1.

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.

Gen-ID: 7321

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades