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ASIC1 Antikörper (AA 332-460) (FITC)

Der Kaninchen Polyklonal Anti-ASIC1-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, ASIC1 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN1395326

Kurzübersicht für ASIC1 Antikörper (AA 332-460) (FITC) (ABIN1395326)

Target

Alle ASIC1 (ACCN2) Antikörper anzeigen
ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))

Reaktivität

  • 77
  • 69
  • 44
  • 10
  • 9
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 80
  • 16
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 83
  • 16
Polyklonal

Konjugat

  • 38
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ASIC1 Antikörper ist konjugiert mit FITC

Applikation

  • 84
  • 35
  • 24
  • 15
  • 12
  • 11
  • 11
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 11
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 332-460

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ACCN2/ASIC1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))

    Andere Bezeichnung

    ACCN2

    Hintergrund

    Synonyms: ASIC1, ACCN2, ACCN2_HUMAN, Acid sensing ion channel 1, Acid sensing ion channel 1a protein, Acid sensing ion channel, Acid-sensing ion channel 1, AI843610, Amiloride sensitive cation channel 2 neuronal, Amiloride-sensitive cation channel 2, ASIC, ASIC1, ASIC1A, B530003N02Rik, BNAC2, Brain sodium channel 2, Cation channel amiloride sensitive neuronal 2, hBNaC2, neuronal.

    Background: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.

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