Serotonin Receptor 1E Antikörper (AA 1-120) (Biotin)

Produktnummer ABIN1394851

Produktdetails anti-Serotonin Receptor 1E Antikörper (Biotin)

Target: Serotonin Receptor 1E (HTR1E)

Bindungsspezifität: AA 1-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1E Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Cow,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Serotonin Receptor 1E

Target: Serotonin Receptor 1E (HTR1E)

Andere Bezeichnung: 5HT1E Receptor/SR-1E (HTR1E Produkte)

Synonyme: Htr1ea antikoerper, HTR1E antikoerper, 5HT1E antikoerper, 5-HT1E antikoerper, 5-HT-1E antikoerper, 5-hydroxytryptamine (serotonin) receptor 1E antikoerper, 5-hydroxytryptamine receptor 1E antikoerper, 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled antikoerper, Htr1e antikoerper, HTR1E antikoerper, htr1e antikoerper

Hintergrund:

Synonyms: 5 hydroxytryptamine serotonin receptor 1E, 5 hydroxytryptamine serotonin receptor 1E G protein coupled, 5 hydroxytryptamine 1E receptor, 5-HT-1E, 5-hydroxytryptamine receptor 1E, HTR1E, S31, Serotonin receptor 1E, 5HT1E_HUMAN.

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process