Serotonin Receptor 1E Antikörper (AA 70-150)

Produktnummer ABIN7217098

Der Kaninchen Polyklonal anti-Serotonin Receptor 1E Antikörper wird verwendet zum Nachweis von Serotonin Receptor 1E in Proben von Human. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für Serotonin Receptor 1E Antikörper (AA 70-150) (ABIN7217098)

Target: Serotonin Receptor 1E (HTR1E)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1E Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Serotonin Receptor 1E Antikörper

Bindungsspezifität: AA 70-150

Verwendungszweck: Rabbit Anti-SR-1E Polyclonal Antibody

Spezifität: SR-1E Polyclonal Antibody detects endogenous levels of SR-1E protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SR-1E at AA range: 70-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF/ICC1:50-300,ELISA 1:2000-20000,IHC 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Serotonin Receptor 1E

Target: Serotonin Receptor 1E (HTR1E)

Andere Bezeichnung: SR-1E

Hintergrund: HTR1E, 5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, S31, Serotonin receptor 1EHTR1E (5-Hydroxytryptamine Receptor 1E) is a Protein Coding gene. Diseases associated with HTR1E include attention deficit-hyperactivity disorder. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and serotonin binding. An important paralog of this gene is HTR1F. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Serotonin 5-ht1E receptors are primarily located in the frontal cortex, caudate putamen, claustrum, hippocampus, and amygdala. The human 5-ht1E receptor gene has been localized to chromosome 6 (6q14-q15), the receptor is closely related to the serotonin 5-HT1F receptor.

Molekulargewicht: 42kD

Gen-ID: 3354

UniProt: P28566

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process