DUSP6 Antikörper (FITC)

Produktnummer ABIN1391912

Produktdetails anti-DUSP6 Antikörper (FITC)

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP6 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-DUSP6 Antikörper (FITC) (ABIN1391912)

Li, Zhou, Ying, Shi, Cheng, Ren, Griffin, Jia, Li, Moorman, Yao: "Hepatitis C virus-induced reduction in miR-181a impairs CD4(+) T-cell responses through overexpression of DUSP6." in: Hepatology (Baltimore, Md.), (2015) (PubMed).

Details zu DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Andere Bezeichnung: Dusp6/Mkp-3 (DUSP6 Produkte)

Synonyme: HH19 antikoerper, MKP3 antikoerper, PYST1 antikoerper, 1300019I03Rik antikoerper, MKP-3 antikoerper, Mkp3 antikoerper, wu:fd99d09 antikoerper, mkp3 antikoerper, pyst1 antikoerper, DUSP6 antikoerper, dusp6 antikoerper, dual specificity phosphatase 6 antikoerper, dual specificity phosphatase 6 L homeolog antikoerper, Dual specificity protein phosphatase 6 antikoerper, DUSP6 antikoerper, Dusp6 antikoerper, dusp6 antikoerper, dusp6.L antikoerper, dus6 antikoerper

Hintergrund:

Synonyms: Dual specicity phosphatase 6, Dual specicity phosphatase 6 isoform a, Dual specicity protein phosphatase 6, Dual specicity protein phosphatase PYST1, DUS6_HUMAN, DUSP 6, DUSP 6a, Dusp6, DUSP6a, MAP kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, Mitogen-activated protein kinase phosphatase 3, MKP 3, MKP-3, MKP3, PYST 1, PYST1, Serine/threonine specic protein phosphatase.

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.

Gen-ID: 8642

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades