ZNF148 Antikörper (AA 303-380)
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- Target Alle ZNF148 Antikörper anzeigen
- ZNF148 (Zinc Finger Protein 148 (ZNF148))
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Bindungsspezifität
- AA 303-380
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF148 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZNF148/ZBP-89
- Isotyp
- IgG
- Top Product
- Discover our top product ZNF148 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ZNF148 (Zinc Finger Protein 148 (ZNF148))
- Andere Bezeichnung
- ZNF148/ZBP-89 (ZNF148 Produkte)
- Synonyme
- BERF-1 antikoerper, BFCOL1 antikoerper, HT-BETA antikoerper, ZBP-89 antikoerper, ZFP148 antikoerper, pHZ-52 antikoerper, 2210405J08Rik antikoerper, AI480666 antikoerper, AW045217 antikoerper, Znf148 antikoerper, Zbp-89 antikoerper, fb06h05 antikoerper, wu:fb06h05 antikoerper, zfp149 antikoerper, zgc:165342 antikoerper, SLC12A8 antikoerper, zinc finger protein 148 antikoerper, ZNF148 antikoerper, Zfp148 antikoerper, znf148 antikoerper
- Hintergrund
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Synonyms: Transcription factor ZBP-89, Transcription factor ZBP89, ZBP89, Zinc finger DNA binding protein 89, Zinc finger DNA-binding protein 89, Zinc finger protein 148, ZN148_HUMAN, ZNF 148, ZNF148.
Background: ZNF148 is a zinc finger transcription factor that is universally expressed. ZBP-89, a Kruppel-like repressor protein, is the silencer element binding factor for Vimentin. ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1). ZBP-89 expression is induced by trans-retinoic acid or butyrate, which also induces terminal differentiation of colon cancer cells. ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53. ZBP-89 also regulates cell proliferation, in part, through its ability to directly bind the p53 protein and retard its nuclear export. Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells.
- Gen-ID
- 7707
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