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LAT Antikörper (pTyr161)

Der Kaninchen Polyklonal Anti-LAT-Antikörper wurde für ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, LAT in Proben von Human zu detektieren.
Produktnummer ABIN1386362

Kurzübersicht für LAT Antikörper (pTyr161) (ABIN1386362)

Target

Alle LAT Antikörper anzeigen
LAT (Linker For Activation of T Cells (LAT))

Reaktivität

  • 129
  • 50
  • 33
  • 1
Human

Wirt

  • 114
  • 20
  • 2
  • 1
Kaninchen

Klonalität

  • 114
  • 23
Polyklonal

Konjugat

  • 79
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Dieser LAT Antikörper ist unkonjugiert

Applikation

  • 88
  • 47
  • 38
  • 38
  • 23
  • 22
  • 14
  • 12
  • 8
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 20
    • 15
    • 14
    • 10
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr161

    Homologie

    Human,Mouse,Rat,Cow

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    LAT (Linker For Activation of T Cells (LAT))

    Andere Bezeichnung

    LAT

    Hintergrund

    Synonyms: LAT1, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38, LAT

    Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

    Gen-ID

    27040

    UniProt

    O43561

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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