PIGA Antikörper

Produktnummer ABIN1386146

Der Kaninchen Polyklonal anti-PIGA Antikörper wird verwendet zum Nachweis von PIGA in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF (p) und IHC (p).

Kurzübersicht für PIGA Antikörper (ABIN1386146)

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PIGA Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIGA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PIGA

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Andere Bezeichnung: PIGA

Hintergrund:

Synonyms: GlcNAc PI synthesis protein, GlcNAc-PI synthesis protein, GPI3, Phosphatidylinositol glycan anchor biosynthesis class A, phosphatidylinositol glycan anchor biosynthesis, class A paroxysmal nocturnal hemoglobinuria, Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, PIG A, PIG-A, PIGA_HUMAN, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A.

Background: PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure.

Gen-ID: 5277

Pathways: Inositol Metabolic Process