UBE2D1 Antikörper (AA 81-147)

Produktnummer ABIN1385616

Dieser Anti-UBE2D1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von UBE2D1 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für UBE2D1 Antikörper (AA 81-147) (ABIN1385616)

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-UBE2D1 Antikörper

Bindungsspezifität: AA 81-147

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2D1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2D1

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Andere Bezeichnung: UBE2D1

Hintergrund:

Synonyms: E217KB1, SFT, Stimulator of Fe transport, UB2D1_HUMAN, UBC 4/5, UBC4/5, UBC4/5 homolog, UBCH 5, UBCH 5A, UBCH5, UBCH5A, Ube2d1, Ubiquitin carrier protein, Ubiquitin carrier protein D1, Ubiquitin conjugating enzyme E2 17 kDa 1, Ubiquitin conjugating enzyme E2 D1, Ubiquitin conjugating enzyme E2D 1 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2D 1, Ubiquitin protein ligase D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E217KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1.

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.

Gen-ID: 7321

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades