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Nitrotyrosine Antikörper Primary Antibody

Reaktivität: Human, Maus, Ratte ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (5 references)
Produktnummer ABIN1385080
$374.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target Alle Nitrotyrosine Antikörper anzeigen
    Nitrotyrosine
    Reaktivität
    • 15
    • 15
    • 15
    • 1
    Human, Maus, Ratte
    Wirt
    • 33
    • 24
    • 8
    Kaninchen
    Klonalität
    • 32
    • 32
    Polyklonal
    Konjugat
    • 31
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Nitrotyrosine Antikörper ist unkonjugiert
    Applikation
    • 49
    • 32
    • 25
    • 23
    • 22
    • 16
    • 13
    • 12
    • 12
    • 11
    • 10
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated to Nitrotyrosine
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Li, Du, Yuan, Han, Dong, Chen, Wu, Zhang, Xu, Han, Zhang, Xia: "Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity." in: Free radical biology & medicine, Vol. 110, pp. 102-116, (2017) (PubMed).

    Zhang, Song, Pang, Zhang, Wan, Yuan, Wu, Liu: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, (2015) (PubMed).

    Chen, Kan: "Down-regulation of superoxide dismutase 1 by PMA is involved in cell fate determination and mediated via protein kinase D2 in myeloid leukemia cells." in: Biochimica et biophysica acta, Vol. 1853, Issue 10 Pt A, pp. 2662-75, (2015) (PubMed).

    Wang, Su, Wang, Zhang, Zhang, Niu, Guo, Li, Jiang, Liu, Guo: "Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes." in: American journal of translational research, Vol. 7, Issue 10, pp. 1724-35, (2015) (PubMed).

    Vendrov, Vendrov, Smith, Yuan, Sumida, Robidoux, Runge, Madamanchi: "NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease." in: Antioxidants & redox signaling, (2015) (PubMed).

  • Target
    Nitrotyrosine
    Abstract
    Nitrotyrosine Produkte
    Substanzklasse
    Chemical
    Hintergrund

    Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.

    Subcellular location: Cytoplasm

    Synonyms: NULL

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