EGFR Antikörper
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- Target Alle EGFR Antikörper anzeigen
- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser EGFR Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Spezifität
- Anti-human Receptor tyrosine-protein kinase ErbB-1 (EGFR)
- Produktmerkmale
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Aufreinigung
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human ErbB-1
- Klon
- DP-4A1
- Isotyp
- IgG1
- Top Product
- Discover our top product EGFR Primärantikörper
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anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 7A6F12 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C4 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibodyEGFR Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 688CT33-1-3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reaktivität: Human, Maus, Ratte, Schwein, Affe, Rind (Kuh), Huhn, Hund, Pferd, Kaninchen, Meerschweinchen, Avian, Cat, Esel, Ziege, Hamster, Schaf WB Wirt: Ziege Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibodyEGFR Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 5E10D3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibodyEGFR Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reaktivität: Human, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: EGFR
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Andere Bezeichnung
- ErbB1 (EGFR Produkte)
- Hintergrund
- Epidermal growth factor receptor (EGFR, ErbB-1) is a 170-kDa transmembrane glycoprotein encoded by the HER1 proto-oncogene. It belongs to the EGFR family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her3 (ErbB-3) and Her4 (ErbB-4). ErbB-1 is expressed on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα). Growth factor binding to the extracellular domain of ErbB-1 induces formation of homo- and heterodimers with another member of the ErbB receptor family. The EGFR signaling pathway is one of the most important pathways that regulate growth, survival, proliferation and differentiation in mammalian cells, while over-expression of ErbB-1 have been associated with a number of cancers, including lung cancer and glioblastoma.
- UniProt
- P00533
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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