CD74 Antikörper (Biotin)

Produktnummer ABIN135827

Der Maus Monoklonal Anti-CD74-Antikörper wurde für FACS validiert. Er ist geeignet, CD74 in Proben von Human zu detektieren.

Kurzübersicht für CD74 Antikörper (Biotin) (ABIN135827)

Target: CD74 (HLA-DR-gamma (CD74))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD74 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: LN2

Produktdetails anti-CD74 Antikörper (Biotin)

Spezifität: Human CD74, Mr 41, 35, 33 kDa

Produktmerkmale: Mouse Anti-Human CD74-BIOT

Aufreinigung: Ion exchange column

Immunogen: Cell line SU-DHL-4 nuclei

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD74

Target: CD74 (HLA-DR-gamma (CD74))

Andere Bezeichnung: CD74

Hintergrund: CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface.

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints