ITGAL Antikörper

Produktnummer ABIN135680

Der Maus Monoklonal Anti-ITGAL-Antikörper wurde für FACS validiert. Er ist geeignet, ITGAL in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ITGAL Antikörper (ABIN135680)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 38

Produktdetails anti-ITGAL Antikörper

Spezifität: Human CD11a, Mr 180 kDa

Produktmerkmale: Mouse Anti-Human CD11a-UNLB

Aufreinigung: Purified

Immunogen: Fibronectin purified monocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature , ELISA - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

Blocking studies, cell adhesion, cytotoxicity

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-ITGAL Antikörper (ABIN135680)

Jung, Zhou, Iden, Bischoff, Qu: "T cell stiffness is enhanced upon formation of immunological synapse." in: eLife, Vol. 10, (2021) (PubMed).

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a

Hintergrund: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1), represents the 180 kDa integrin L subunit which combines with the CD18 2 integrin subunit to form the L2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

Pathways: Activated T Cell Proliferation, Integrin Complex