CTLA4 Antikörper

Produktnummer ABIN135317

Der Hamster Monoklonal Anti-CTLA4-Antikörper wurde für ELISA validiert. Er ist geeignet, CTLA4 in Proben von Maus zu detektieren.

Kurzübersicht für CTLA4 Antikörper (ABIN135317)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1B8

Produktdetails anti-CTLA4 Antikörper

Spezifität: Mouse CD152, Mr 33-37 kDa

Produktmerkmale: Hamster Anti-Mouse CD152-LE/AF

Endotoxin-Niveau: Low endotoxin

Immunogen: Extracellular portion of murine CTLA-4 fused to a murine IgG2a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: ELISA - Quality tested , FLISA - Quality tested FC - Reported literature , Stim - Reported in literature
• Working Dilutions: ELISA BIOT conjugate 1:5,000 - 1:10,000 FLISA FITC conjugate 1:100 - 1:400 PE conjugate 1 g/mL Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vitro functional studies

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of PBS

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152

Hintergrund: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.

Pathways: Cancer Immune Checkpoints