CD38 Antikörper

Produktnummer ABIN135205

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD38 in FACS, IP, ELISA, IHC (fro), Act, St, BR, DD, AD, Sep und CoSt. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD38 Antikörper (ABIN135205)

Target: CD38

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Activation (Act), Stimulation (St), Blocking Reagent (BR), Drug Delivery (DD), Apoptosis Detection (AD), Separation (Sep), Co-Stimulation (CoSt)

Klon: NIMR-5

Produktdetails anti-CD38 Antikörper

Verwendungszweck: Rat Anti-Mouse CD38-LE/AF

Spezifität: Mouse CD38, Mr 42 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD38 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, activation, costimulation, stimulation, apoptosis, drug delivery, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: BCL1 plasma membrane glycoproteins

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD38

Target: CD38

Hintergrund: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.

Gen-ID: 12494

UniProt: P56528