Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

KIT Antikörper (Mast/stem Cell Growth Factor Receptor) (Biotin) Primary Antibody

KIT Reaktivität: Human, Rind (Kuh), Non-Human Primate FACS, ICC, IHC (fro), IP Wirt: Maus Monoclonal 104D2 Biotin
Pubmed (7 references)
Produktnummer ABIN1302740
$417.45
Zzgl. Versandkosten $45.00
0.1 mg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle KIT Antikörper anzeigen
    KIT
    Reaktivität
    • 779
    • 254
    • 66
    • 31
    • 29
    • 25
    • 16
    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    Human, Rind (Kuh), Non-Human Primate
    Wirt
    • 677
    • 141
    • 50
    • 7
    • 2
    • 2
    Maus
    Klonalität
    • 672
    • 208
    Monoklonal
    Konjugat
    • 275
    • 85
    • 82
    • 82
    • 64
    • 64
    • 51
    • 16
    • 14
    • 14
    • 13
    • 13
    • 13
    • 12
    • 10
    • 10
    • 10
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser KIT Antikörper ist konjugiert mit Biotin
    Applikation
    • 454
    • 378
    • 337
    • 174
    • 91
    • 91
    • 82
    • 78
    • 59
    • 52
    • 43
    • 27
    • 17
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    Spezifität
    The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
    HLDA VI, WS Code C-30
    Kreuzreaktivität (Details)
    Human, Non-Human Primates, Bovine
    Immunogen
    MOLM-1 megakaryocytic cells
    Klon
    104D2
    Isotyp
    IgG1
  • Applikationshinweise
    Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry.
    Kommentare

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Stevenson, McGlynn, Hodge, McLinden, George, Davies, Shiels: "Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations." in: Stem cells and development, Vol. 18, Issue 10, pp. 1389-98, (2009) (PubMed).

    Wihlidal, Varga, Pfeilstöcker, Karlic: "Expression and functional significance of osteocalcin splicing in disease progression of hematological malignancies." in: Leukemia research, Vol. 30, Issue 10, pp. 1241-8, (2006) (PubMed).

    Blair, Sutherland: "Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)." in: Experimental hematology, Vol. 28, Issue 6, pp. 660-71, (2000) (PubMed).

    Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, (2000) (PubMed).

    Broudy, Lin, Liles, Corey, OLaughlin, Mou, Linnekin: "Signaling via Src family kinases is required for normal internalization of the receptor c-Kit." in: Blood, Vol. 94, Issue 6, pp. 1979-86, (1999) (PubMed).

    Broudy, Lin, Bühring, Komatsu, Kavanagh: "Analysis of c-kit receptor dimerization by fluorescence resonance energy transfer." in: Blood, Vol. 91, Issue 3, pp. 898-906, (1998) (PubMed).

    Rappold, Ziegler, Köhler, Marchetto, Rosnet, Birnbaum, Simmons, Zannettino, Hill, Neu, Knapp, Alitalo, Alitalo, Ullrich, Kanz, Bühring: "Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase." in: Blood, Vol. 90, Issue 1, pp. 111-25, (1997) (PubMed).

  • Target
    KIT
    Andere Bezeichnung
    CD117 (KIT Produkte)
    Synonyme
    C-Kit, CD117, PBT, SCFR, Bs, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT, c-kit, MGF, KIT, C-KIT, kit, receptor, sparse, Xkl-1, kit-a, kit-b, kl1-A, krk1, pbt, scfr, KIT proto-oncogene receptor tyrosine kinase, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a, KIT proto-oncogene receptor tyrosine kinase S homeolog, KIT, Kit, kita, kit, kit.S
    Hintergrund
    CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Sie sind hier:
help Kundenservice