DPP4 Antikörper (APC)

Produktnummer ABIN1302631

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DPP4 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DPP4 Antikörper (APC) (ABIN1302631)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: BA5b

Produktdetails anti-DPP4 Antikörper (APC)

Verwendungszweck: Anti-Hu CD26 APC

Spezifität: The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: A human T cell clone

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.
Avoid prolonged exposure to light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: CD26

Hintergrund: Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

Gen-ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity