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Nitrotyrosine Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Nitrotyrosine in WB, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Diverse Spezies.
Produktnummer ABIN1302502

Kurzübersicht für Nitrotyrosine Antikörper (ABIN1302502)

Target

Alle Nitrotyrosine Antikörper anzeigen
Nitrotyrosine

Reaktivität

  • 20
  • 16
  • 16
  • 1
Diverse Spezies

Wirt

  • 24
  • 21
  • 5
Maus

Klonalität

  • 26
  • 24
Monoklonal

Konjugat

  • 21
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Nitrotyrosine Antikörper ist unkonjugiert

Applikation

  • 48
  • 28
  • 25
  • 20
  • 18
  • 14
  • 13
  • 13
  • 10
  • 10
  • 7
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

EM-30
  • Verwendungszweck

    Anti-Nitrotyrosine Purified

    Spezifität

    The antibody EM-30 detects nitrotyrosine group in biological material. It can be used as a marker for peroxynitrite formation in particular tissues.

    Kreuzreaktivität (Details)

    Broad

    Aufreinigung

    Purified by protein-A affinity chromatography.

    Reinheit

    > 95 % (by SDS-PAGE)

    Immunogen

    NO2-Tyr-CH2-Thyroglobulin

    Isotyp

    IgG1
  • Applikationshinweise

    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia.
    Immunohistochemistry (frozen sections): Recommended dilution: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia.
    Western blotting: positive control: NO2-BSA, NO2-HSA.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Target

    Nitrotyrosine

    Substanzklasse

    Chemical

    Hintergrund

    Nitrotyrosine can be detected in proteins from a variety of tissues usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.,TyrNO2, C9H10N2O5
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