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CCDC98 Antikörper (Family with Sequence Similarity 175, Member A) AA 1-313 Primary Antibody

FAM175A Reaktivität: Human FACS, IP, WB Wirt: Maus Monoclonal ABRA1-01 unconjugated
Produktnummer ABIN1302443
$417.45
Zzgl. Versandkosten $45.00
0.1 mg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle CCDC98 (FAM175A) Antikörper anzeigen
    CCDC98 (FAM175A)
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-313
    Reaktivität
    • 22
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 3
    Maus
    Klonalität
    • 35
    • 3
    Monoklonal
    Konjugat
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC98 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 13
    • 10
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
    Spezifität
    The mouse monoclonal antibody ABRA1-01 recognizes N-terminal part of ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
    Kreuzreaktivität (Details)
    Human, Other not tested
    Aufreinigung
    Purified by protein-A affinity chromatography
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
    Klon
    ABRA1-01
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Target
    CCDC98 (FAM175A)
    Andere Bezeichnung
    ABRA1 (FAM175A Produkte)
    Synonyme
    CCDC98, abra1, ccdc98, fam175a, ABRA1, 3830405G04Rik, 5630400M01Rik, AI506069, AL024423, AV118690, Ccdc98, RGD1305287, zgc:103522, abraxas 1, BRCA1 A complex subunit, Coiled-coil domain-containing protein 98, BRCA1 A complex subunit, family with sequence similarity 175 member A, abraxas 2a, BRISC complex subunit, abraxas 1, BRCA1 A complex subunit S homeolog, ABRAXAS1, abraxas1, Abraxas1, FAM175A, abraxas2a, abraxas1.S
    Hintergrund
    ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.
    Pathways
    DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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