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Mre11 Antikörper (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae)) AA 68-706 Primary Antibody

MRE11A Reaktivität: Maus ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129662
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle Mre11 (MRE11A) Antikörper anzeigen
    Mre11 (MRE11A)
    Bindungsspezifität
    • 17
    • 15
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 68-706
    Reaktivität
    • 83
    • 57
    • 44
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 93
    • 7
    Kaninchen
    Klonalität
    • 87
    • 13
    Polyklonal
    Konjugat
    • 52
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Mre11 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 36
    • 27
    • 26
    • 26
    • 21
    • 16
    • 14
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corres-ponding to amino acids 68-706 of mouse Mre11 protein.
    Immunogentype:Recombinant
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80 kDa in size corresponding to Mre11 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.05 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Mre11 (MRE11A)
    Andere Bezeichnung
    Mre11 (MRE11A Produkte)
    Synonyme
    wu:faa63d12, zgc:64018, Mre11, Mre11b, ATLD, HNGS1, MRE11, MRE11B, MRE11 homolog A, double strand break repair nuclease, MRE11 homolog, double strand break repair nuclease, MRE11A homolog A, double strand break repair nuclease, mre11a, MRE11, Mre11a
    Hintergrund
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Mre11 is a component of the MRN complex (Mre11/Rad50/Nbs1), which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may
    Synonyms: AT like disease antibody, Ataxia telangiectasia disorder like antibody, Ataxia-telangiectasia disorder-like antibody, ATLD antibody, DNA recombination and repair protein antibody
    Gen-ID
    4361, 18202590
    UniProt
    Q61216
    Pathways
    DNA Reparatur
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