Mre11 Antikörper (AA 575-600)

Produktnummer ABIN129647

Hersteller Produkt- Nr.: 600-401-872

Produktdetails anti-Mre11 Antikörper

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Bindungsspezifität: AA 575-600

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mre11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Hersteller Produkt- Nr.: 600-401-872

Hersteller: Rockland

Verwendungszweck: Mre11 Antibody

Kreuzreaktivität (Details): This affinity-purified antibody is directed against Saccharomyces cerevisiae Mre11 protein.

Produktmerkmale: Synonyms: rabbit anti-Mre11 antibody, Double-strand break repair protein MRE11, DNA recombination and repair protein, Meiotic recombination 11

Aufreinigung: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 575-600 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: This affinity purified antibody has been tested for use in ELISA and by ChIP assay.  Specific conditions for reactivity should be optimized by the end user.

ChIP Dilution: User Optimized

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.19 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Andere Bezeichnung: MRE11 (MRE11A Produkte)

Hintergrund: Background: Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability.  Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function.  This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.

Gen-ID: 4361, 6323880

UniProt: P32829

Pathways: DNA Reparatur