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ATF3 Antikörper (Activating Transcription Factor 3) AA 113-130 Primary Antibody

ATF3 Reaktivität: Human FM, IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN129602
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle ATF3 Antikörper anzeigen
    ATF3
    Bindungsspezifität
    • 16
    • 15
    • 11
    • 9
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 113-130
    Reaktivität
    • 67
    • 29
    • 27
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 56
    • 12
    Kaninchen
    Klonalität
    • 58
    • 10
    Polyklonal
    Konjugat
    • 35
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATF3 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 33
    • 32
    • 15
    • 13
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Fluorescence Microscopy (FM), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This antibody was produced from a synthetic peptide corresponding to aa 113-130 of human ATF3.
    Isotyp
    IgG
  • Applikationshinweise
    Affinity purified anti-ATF3 has been tested by ELISA and western blotting against recombinant forms of the protein. Although not tested, this antibody is likely function in most immunoassays including immunofluorescence microscopy, immunohistochemistry.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Xie, Xu, Wu, Shen, Zhao, Du, Lv, Gu, Pan, Xu, Xie, Li: "Involvement of CYR61 and CTGF in the fascin-mediated proliferation and invasiveness of esophageal squamous cell carcinomas cells." in: The American journal of pathology, Vol. 176, Issue 2, pp. 939-51, (2010) (PubMed).

  • Target
    ATF3
    Andere Bezeichnung
    ATF3 (ATF3 Produkte)
    Synonyme
    zgc:55526, ATF3, LRG-21, LRF-1, LRFI, atf-3, activating transcription factor 3, activating transcription factor 3 L homeolog, atf3, ATF3, Atf3, atf3.L
    Hintergrund
    ATF3, or Activating Transcription Factor 3, is a member of mammalian activation TF/CREB protein family of transcription factors. ATF3 binds the cAMP response element (cre) (consensus: 5'-gtgacgt[ac][ag]-3'), a sequence present in many viral and cellular promoters. However, ATF3 represses rather than activates transcription from promoters with ATF sites stabilizing inhibitory co-factors at the promoter.  Alternate splicing forms of ATF3, called ATF3 delta Zip, lack the leucine zipper domain and do not bind DNA.  ATF3 delta Zip stimulates transcription, presumably by sequestering inhibitory co-factors away from the promoter.  Human ATF3 (SwissProt 18847) is a 20575 Da protein composed of 181 amino acids.
    Synonyms: Cyclic AMP-dependent transcription factor ATF-3 cAMP-dependent transcription factor ATF-3 Activating transcription factor 3
    Gen-ID
    467
    UniProt
    P18847
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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