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PLK1 Antikörper (Polo-Like Kinase 1) pThr210 Primary Antibody

PLK1 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN129581
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle PLK1 Antikörper anzeigen
    PLK1
    Bindungsspezifität
    • 20
    • 19
    • 15
    • 12
    • 11
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 205-214, pThr210
    Reaktivität
    • 150
    • 58
    • 54
    • 9
    • 9
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 117
    • 25
    • 9
    • 1
    Kaninchen
    Klonalität
    • 128
    • 24
    Polyklonal
    Konjugat
    • 86
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PLK1 Antikörper ist unkonjugiert
    Applikation
    • 107
    • 67
    • 47
    • 28
    • 27
    • 26
    • 22
    • 19
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Aufreinigung
    This product is an affinity purified antibody produced by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
    Immunogen
    Anti-Polo-like Kinase pT210 Antibody was produced by repeated immunizations with a synthetic phospho peptide corresponding to aa 205-214 of Human Polo-like kinase 1 (Plk1) protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity-purified antibody has been tested for use in ELISA, IHC and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 68 kDa in size corresponding to Plk-1 by western blotting in the appropriate cell lysate or extract.   This antibody is positive by IHC on kidney, liver, cancer, thyroid and lymphocyte tissue.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Adler, Müller, Rached, Dekant, Mally: "Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity." in: Carcinogenesis, Vol. 30, Issue 4, pp. 711-9, (2009) (PubMed).

  • Target
    PLK1
    Andere Bezeichnung
    Plk1 (PLK1 Produkte)
    Synonyme
    PLK, STPK13, plk, PLK-1, Plx1, stpk13, Plk, cb525, cb636, ik:tdsubc_2d1, wu:fb37g11, wu:fb76g03, xx:tdsubc_2d1, polo like kinase 1, polo like kinase 1 S homeolog, polo-like kinase 1, polo-like kinase 1 (Drosophila), Serine/threonine-protein kinase plk-1, PLK1, plk1.S, plk1, Plk1, plk-1
    Hintergrund
    Polo-like Kinase pT210 Antibody detects phosphorylated Plk1 protein. Polo-like kinase 1, also known as Plk-1, serine-threonine protein kinase 13 and STPK13, may be required for cell division and have a role during G1 or S phase and is associated with the phosphorylation of cyclin B1.  Phosphorylation of Plk-1 on T210 contributes to proper mitotic progression.  Plk-1 has a nuclear localization and accumulates to a maximum during the G2 and M phases, declines to a nearly undetectable level following mitosis and throughout G1 phase, and then begins to accumulate again during S phase.  Plk-1 is a member of the Ser/Thr protein kinase family and the CDC5/Polo subfamily and contains 2 POLO box domains.
    Synonyms: PLK 1 antibody, PLK antibody, polio like kinase antibody, Polo like kinase 1 antibody, Polo-like kinase 1 antibody, Serine/threonine protein kinase 13 antibody
    Gen-ID
    5347, 21359873
    UniProt
    P53350
    Pathways
    Zellzyklus, M Phase
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