Integrin Alpha2b Antikörper (FITC)
Kurzübersicht für Integrin Alpha2b Antikörper (FITC) (ABIN127332)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Produktmerkmale
- Molar Ratio: 15-25 moles of FITC per mole Ig.
-
Aufreinigung
- Ion Exchange or Affinity Chromatography.
-
Immunogen
- Washed Human platelets. Remarks: Myeloma cells with spleen cells from Balb/c mice.
-
Isotyp
- IgG1
-
-
anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p), Func Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) (AA 122-171) antibodyCD41 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
Studies of platelet functions. Identification of gpIIb. Immunohistochemistry on frozen sections or cell smears: 1: 50-1: 100 dilution. Fluorescence Microscopy or Flow Cytometry (20 l/10^6 platelets/test).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- PBS containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
-
-
- Integrin Alpha2b (CD41)
-
Andere Bezeichnung
- CD41 / ITGA2B
-
Hintergrund
- The CD41 antigen (platelet GPIIb, alpha IIb integrin) is a Glycoprotein composed of 2 chains, GPIIb alpha (120 kDa) and GPIIb beta (23 kDa), linked by one disulfide bond. (1) CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. The structure and role of the complex CD41/CD61 in hemostasis is reviewed in Ref.2. CD41 is expressed by platelets, Megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the Megakaryocytic lineage. (3) It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on Human Leucocyte Differentiation Antigens in Boston, in 1993.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
-
Gen-ID
- 9606
-
UniProt
- P08514
-
Pathways
- Integrin Complex
Target
-
