Integrin Alpha2b Antikörper (FITC)

Produktnummer ABIN127332

Dieses Anti-Integrin Alpha2b-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Integrin Alpha2b in FACS, IF und IHC (fro). Geeignet für Human.

Kurzübersicht für Integrin Alpha2b Antikörper (FITC) (ABIN127332)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: SZ-22

Produktdetails anti-Integrin Alpha2b Antikörper (FITC)

Produktmerkmale: Molar Ratio: 15-25 moles of FITC per mole Ig.

Aufreinigung: Ion Exchange or Affinity Chromatography.

Immunogen: Washed Human platelets. Remarks: Myeloma cells with spleen cells from Balb/c mice.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Studies of platelet functions. Identification of gpIIb. Immunohistochemistry on frozen sections or cell smears: 1: 50-1: 100 dilution. Fluorescence Microscopy or Flow Cytometry (20 l/10^6 platelets/test).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41 / ITGA2B

Hintergrund: The CD41 antigen (platelet GPIIb, alpha IIb integrin) is a Glycoprotein composed of 2 chains, GPIIb alpha (120 kDa) and GPIIb beta (23 kDa), linked by one disulfide bond. (1) CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. The structure and role of the complex CD41/CD61 in hemostasis is reviewed in Ref.2. CD41 is expressed by platelets, Megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the Megakaryocytic lineage. (3) It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on Human Leucocyte Differentiation Antigens in Boston, in 1993.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

Gen-ID: 9606

UniProt: P08514

Pathways: Integrin Complex