KISS1 Antikörper (N-Term)

Produktnummer ABIN127218

Der Kaninchen Polyklonal anti-KISS1 Antikörper (ABIN127218) detektiert spezifisch KISS1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für KISS1 Antikörper (N-Term) (ABIN127218)

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KISS1 Antikörper

Bindungsspezifität: N-Term

Spezifität: The antibody recognizes 16 kDa human KiSS-1.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide near the N-terminus of Mouse KiSS-1.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu KISS1

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Andere Bezeichnung: KiSS-1

Hintergrund: KiSS-1 has been reported to suppress metastases of melanomas and breast carcinomas without affecting tumorigenicity. Human KiSS-1 transcripts are predominately expressed in the brain and placenta. Expression of KiSS-1 reduces the level of NFκB p50/p65 binding to the MMP9 promoter and correlates with diminished expression of the 92 kDa type IV collagenase (MMP-9). KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization.Synonyms: KISS1, Metastasis-suppressor KiSS-1, PP5098

Gen-ID: 3814

NCBI Accession: NP_002247

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion