TLR1 Antikörper

Produktnummer ABIN127125

Dieses Anti-TLR1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von TLR1 in WB und EIA. Geeignet für Human.

Kurzübersicht für TLR1 Antikörper (ABIN127125)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TLR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR1 Antikörper

Aufreinigung: Antigen affinity chromatography

Immunogen: Recombinant human TLR1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 200 - 1: 1000. ELISA: 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Details zu TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Andere Bezeichnung: CD281 / TLR1

Hintergrund: The TLR (toll-like receptors) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFκB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater that 65 % sequence identity, and, like other members of TLR family, it induces NFκB signaling upon activation.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

Gen-ID: 9606

UniProt: Q15399

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades