ENOS Antikörper (pSer1177)
Kurzübersicht für ENOS Antikörper (pSer1177) (ABIN126844)
Target
Alle ENOS (NOS3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer1177
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Spezifität
- This antibody specifically recognizes eNOS phosphorylated at Serine 1177.
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Produktmerkmale
- Synonyms: Endothelial NOS, EC-NOS, NOS type III, Constitutive NOS, eNOS, Nitric oxide synthase,endothelial
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Aufreinigung
- Subsequent Ultrafiltration and Size Exclusion Chromatography
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Immunogen
- Synthetic phosphopeptide conjugated to KLH
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Isotyp
- IgG1
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Applikationshinweise
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from pervanadate treated Bend3 cells. ELISA: 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide, 50 % Glycerol, PEG and Sucrose
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
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Andere Bezeichnung
- NOS3
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Hintergrund
- Endothelial NO synthase (eNOS) produces nitric oxid (NO) which plays a crucial role in cardiovascular homeostasis. Activation of the enzyme and NO production can be induced by phosphorylation of eNOS at serine 1177 by activated Akt/PKB.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial
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Gen-ID
- 4846
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UniProt
- P29474
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Pathways
- ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
Target
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