CD40 Ligand Antikörper

Produktnummer ABIN121931

Der Ziege Polyklonal anti-CD40 Ligand Antikörper wird verwendet zum Nachweis von CD40 Ligand in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für CD40 Ligand Antikörper (ABIN121931)

Target: CD40 Ligand (CD40LG)

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CD40 Ligand Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CD40 Ligand Antikörper

Spezifität: This antibody is specific for the soluble form of human CD154, also designated CD40L (sCD40 Ligand), a member of the TNF receptor superfamily, comprising the full-length of the TNF homologous region of CD154.

Aufreinigung: Affinity chromatography

Immunogen: Recombinant human soluble CD154

Anwendungsinformationen

Applikationshinweise: ELISA (direct ELISA, 0.5 μg/mL). Western blot (0.1 - 0.2 μg).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.1 mL distilled water.

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4, containing no preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2 - 8 °C and reconstituted (undiluted) at -20 °C. Avoid repeated freezing and thawing. For long term storage the addition of 0.09 % sodium azide is recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: One year from despatch.Reconstitution: Restore with 0.1 ml distilled water..

Haltbarkeit: 12 months

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154 / CD40L

Hintergrund: CD154 is expressed predominantly on activated CD4+ T lymphocytes, and acts as a costimulatory molecule in B cell differentiation/proliferation, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, and cytokines secreted by activated T cells.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

Gen-ID: 959

UniProt: P29965

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints