FEN1 Antikörper (N-Term)

Produktnummer ABIN121840

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FEN1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FEN1 Antikörper (N-Term) (ABIN121840)

Target: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FEN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-FEN1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is specific for Flap Structure-specific Endonuclease 1 (FEN1).

Aufreinigung: Affinity Chromatography.

Immunogen: Immunogen Synthetic peptide corresponding to a region within the N terminal domain of human FEN1 (locus link ID 2237)

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:5000 - 1:30000, this antibody detects a band of approximately 42 kD in Hela cell lysates. Immunoprecipitation: 4 μg/mg protein - 10 μg/mg protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: TRIS-Citrate/Phosphate pH 7.5 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu FEN1

Target: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Andere Bezeichnung: FEN1 / RAD2

Hintergrund: FEN1 is a member of the XPG/RAD2 endonuclease family which has an important role in lagging strand DNA synthesis and base excision repair. It is hypothesised that FEN1 may play a role in the inhibltion of triplet repeat expansion.Synonyms: DNase IV, FEN-1, Flap endonuclease 1, Flap structure-specific endonuclease 1, MF1, Maturation factor 1

Gen-ID: 2237

UniProt: P39748

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA