IRF5 Antikörper (AA 176-240)

Produktnummer ABIN121152

Dieses Anti-IRF5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IRF5 in WB, IP, IHC (p) und EIA. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für IRF5 Antikörper (AA 176-240) (ABIN121152)

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IRF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 10T1

Produktdetails anti-IRF5 Antikörper

Bindungsspezifität: AA 176-240

Spezifität: The antibody recognizes Human and Mouse Interferon Regulatory Factor 5 (IRF-5). Other species not tested.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human IRF-5 (176-240 aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1/500 - 1/1,000). Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-IRF5 Antikörper (ABIN121152)

Idborg, Zandian, Ossipova, Wigren, Preger, Mobarrez, Checa, Sohrabian, Pucholt, Sandling, Fernandes-Cerqueira, Rönnelid, Oke, Grosso, Kvarnström, Larsson, Wheelock, Syvänen, Rönnblom, Kultima et al.: "Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. ..." in: Frontiers in immunology, Vol. 10, pp. 1029, (2019) (PubMed).

Details zu IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Andere Bezeichnung: IRF5

Hintergrund: IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.Synonyms: IRF-5, Interferon regulatory factor 5

Gen-ID: 3663

UniProt: Q13568

Pathways: TLR Signalweg, Autophagie