Integrin Alpha2b Antikörper

Produktnummer ABIN120752

Der Maus Monoklonal anti-Integrin Alpha2b Antikörper wird verwendet zum Nachweis von Integrin Alpha2b in Proben von Human und Primate. Er wurde validiert für FACS und IHC (fro).

Kurzübersicht für Integrin Alpha2b Antikörper (ABIN120752)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HIP8

Produktdetails anti-Integrin Alpha2b Antikörper

Aufreinigung: Protein-G affinity chromatography

Reinheit: > 95 % (by SDS-PAGE)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: (has been tested by flow cytometric analysis of human platelets. Can be used at less than or equal to 0.5 μg per 100 μL blood (per 10^6 cells). Immunohistochemistry (frozen sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41 / ITGA2B

Hintergrund: CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

UniProt: P08514

Pathways: Integrin Complex