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Integrin beta 2 Antikörper (Biotin)

ITGB2 Reaktivität: Ratte FACS, IHC (fro) Wirt: Maus Monoclonal WT-3 Biotin
Produktnummer ABIN120418
  • Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen
    Integrin beta 2 (ITGB2)
    Reaktivität
    • 199
    • 61
    • 45
    • 10
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 100
    • 95
    • 43
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 147
    • 90
    • 2
    Monoklonal
    Konjugat
    • 109
    • 24
    • 22
    • 16
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin beta 2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 141
    • 85
    • 57
    • 48
    • 41
    • 33
    • 32
    • 26
    • 26
    • 26
    • 22
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This Antibody is specific for the β subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same β subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1
    Klon
    WT-3
    Isotyp
    IgG1
    Top Product
    Discover our top product ITGB2 Primärantikörper
  • Applikationshinweise
    Immunoprecipitation. Flow cytometry. Immunohistochemistry on cryostat sections. Functional studies: in vivo/in vitro.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.2, with 0.09 % NaN3 and 0.5 % BSA.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Integrin beta 2 (ITGB2)
    Andere Bezeichnung
    CD18 / ITGB2 (ITGB2 Produkte)
    Hintergrund
    LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of α and β subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
    Gen-ID
    25021
    NCBI Accession
    NP_036843
    UniProt
    Q9JI30
    Pathways
    NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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