Integrin beta 2 Antikörper (Biotin)
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- Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen
- Integrin beta 2 (ITGB2)
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 2 Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This Antibody is specific for the β subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same β subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1
- Klon
- WT-3
- Isotyp
- IgG1
- Top Product
- Discover our top product ITGB2 Primärantikörper
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- Applikationshinweise
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Immunoprecipitation. Flow cytometry. Immunohistochemistry on cryostat sections. Functional studies: in vivo/in vitro.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.2, with 0.09 % NaN3 and 0.5 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Integrin beta 2 (ITGB2)
- Andere Bezeichnung
- CD18 / ITGB2 (ITGB2 Produkte)
- Hintergrund
- LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of α and β subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
- Gen-ID
- 25021
- NCBI Accession
- NP_036843
- UniProt
- Q9JI30
- Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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