ITGAL Antikörper (Biotin)

Produktnummer ABIN120404

Der Maus Monoklonal anti-ITGAL Antikörper wird verwendet zum Nachweis von ITGAL in Proben von Ratte. Er wurde validiert für FACS und IHC (fro).

Kurzübersicht für ITGAL Antikörper (Biotin) (ABIN120404)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: WT-1

Produktdetails anti-ITGAL Antikörper (Biotin)

Spezifität: This Antibody is specific for the a subunit of LFA-1. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1.

Immunogen: Rat Splenic PHA blasts Donor: BALB/c spleen Fusion Partner: Mouse myeloma cell line PAI

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Flow cytometry. Immunohistochemistry (cryostat sections). Functional studies: in vivo/in vitro
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a / ITGAL

Hintergrund: LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of a and b subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

Gen-ID: 308995

NCBI Accession: NP_001029170

UniProt: Q3T1L6

Pathways: Activated T Cell Proliferation, Integrin Complex