Integrin Alpha2b Antikörper (PE)
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- Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen
- Integrin Alpha2b (CD41)
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin Alpha2b Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody recognises the integrin alpha IIb subunit CD41. Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo. We recommend the use of SM2035A for use in functional studies.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse.
- Aufreinigung
- Affinity Chromatography on Protein G.
- Klon
- MWReg30
- Isotyp
- IgG1
- Top Product
- Discover our top product CD41 Primärantikörper
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IHC (fro), IP, IHC (p) Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IHC (fro), IP, IHC (p), Func Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP8 unconjugated
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- Applikationshinweise
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Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1 mL distilled water
- Konzentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative, 5 % Sucrose and 1 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Target
- Integrin Alpha2b (CD41)
- Andere Bezeichnung
- CD41 / ITGA2B (CD41 Produkte)
- Hintergrund
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation. CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
- Gen-ID
- 16399
- NCBI Accession
- NP_034705
- UniProt
- Q9QUM0
- Pathways
- Integrin Complex
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