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CD46 Antikörper

CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
Produktnummer ABIN119581
  • Target Alle CD46 Antikörper anzeigen
    CD46
    Reaktivität
    • 115
    • 34
    • 20
    • 10
    • 10
    • 3
    Human, Rind (Kuh)
    Wirt
    • 79
    • 54
    • 2
    Maus
    Klonalität
    • 69
    • 66
    Monoklonal
    Konjugat
    • 53
    • 14
    • 14
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD46 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 77
    • 38
    • 35
    • 27
    • 17
    • 14
    • 14
    • 13
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Bovine.
    Aufreinigung
    Affinity Chromatography on Protein A
    Immunogen
    HPB-ALL human T cell line
    Klon
    MEM-258
    Isotyp
    IgG1
    Top Product
    Discover our top product CD46 Primärantikörper
  • Applikationshinweise
    Western blotting (non-reducing conditions). Immunoprecipitation. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Tris buffered saline (TBS) pH ~8.0, 15 mM Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the original vial at 2-8 °C. Freeze stock solution or aliquots thereof at -20 °C.
  • Target
    CD46
    Andere Bezeichnung
    CD46 / MCP (CD46 Produkte)
    Hintergrund
    CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    Gen-ID
    9606
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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