CD46 Antikörper

Produktnummer ABIN119581

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD46 in WB, FACS und IP. Es zeigt Reaktivität gegenüber Proben von Human und Rind (Kuh).

Kurzübersicht für CD46 Antikörper (ABIN119581)

Target: CD46

Reaktivität: Human, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: MEM-258

Produktdetails anti-CD46 Antikörper

Kreuzreaktivität (Details): Species reactivity (tested):Human, Bovine.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: HPB-ALL human T cell line

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blotting (non-reducing conditions). Immunoprecipitation. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Tris buffered saline (TBS) pH ~8.0, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the original vial at 2-8 °C. Freeze stock solution or aliquots thereof at -20 °C.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46 / MCP

Hintergrund: CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen

Gen-ID: 9606

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization