CD46 Antikörper
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Reaktivität
- Human, Rind (Kuh)
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Bovine.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- HPB-ALL human T cell line
- Klon
- MEM-258
- Isotyp
- IgG1
- Top Product
- Discover our top product CD46 Primärantikörper
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- Applikationshinweise
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Western blotting (non-reducing conditions). Immunoprecipitation. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Tris buffered saline (TBS) pH ~8.0, 15 mM Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the original vial at 2-8 °C. Freeze stock solution or aliquots thereof at -20 °C.
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- Target
- CD46
- Andere Bezeichnung
- CD46 / MCP (CD46 Produkte)
- Hintergrund
- CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
- Gen-ID
- 9606
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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