GZMB Antikörper (Biotin)

Produktnummer ABIN119564

Der Maus Monoklonal Anti-GZMB-Antikörper wurde für EIA validiert. Er ist geeignet, GZMB in Proben von Human zu detektieren.

Kurzübersicht für GZMB Antikörper (Biotin) (ABIN119564)

Target: GZMB (Granzyme B (GZMB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GZMB Antikörper ist konjugiert mit Biotin

Applikation: Enzyme Immunoassay (EIA)

Klon: GB10

Produktdetails anti-GZMB Antikörper (Biotin)

Spezifität: This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (SM1806P) as capture reagent.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Purified human Granzyme B. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.001 % Thiomersal

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GZMB

Target: GZMB (Granzyme B (GZMB))

Hintergrund: Ganzyme B which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

Gen-ID: 3002

NCBI Accession: NP_004122

UniProt: P10144

Pathways: Apoptose, Caspase Kaskade in der Apoptose