CD40 Ligand Antikörper

Produktnummer ABIN119172

Dieser Anti-CD40 Ligand Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD40 Ligand in FACS und Func. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für CD40 Ligand Antikörper (ABIN119172)

Target: CD40 Ligand (CD40LG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: MK13A4

Produktdetails anti-CD40 Ligand Antikörper

Spezifität: This antibody recognises the CD154 cell surface antigen. Clone MK13A4 has been reported to block binding of CD40 ligand to its receptor CD40.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Fuctional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Referenzen für anti-CD40 Ligand Antikörper (ABIN119172)

Bose, Dasgupta, Tarafder, Bandyopadhyay: "Microwave-processed nanocrystalline hydroxyapatite: simultaneous enhancement of mechanical and biological properties." in: Acta biomaterialia, Vol. 6, Issue 9, pp. 3782-90, (2010) (PubMed).

Casati, Camisaschi, Novellino, Mazzocchi, Triebel, Rivoltini, Parmiani, Castelli: "Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3782-8, (2008) (PubMed).

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154 / CD40L

Hintergrund: CD154 is a 32kD glycoprotein also known as CD40 ligand. CD154 is expressed on activated T lymphocytes, predominantly CD4+ve cells and also on some basophils and mast cells.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

Gen-ID: 959

NCBI Accession: NP_000065

UniProt: P29965

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints