CTLA4 Antikörper (PE)

Produktnummer ABIN118892

Der Maus Monoklonal Anti-CTLA4 Antikörper wurde für FACS validiert. Er ist geeignet, CTLA4 in Proben von Human zu detektieren.

Kurzübersicht für CTLA4 Antikörper (PE) (ABIN118892)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: BNI3

Produktdetails anti-CTLA4 Antikörper (PE)

Spezifität: This antibody recognises the CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyteassociated antigen 4).

Aufreinigung: Affinity Chromatography

Immunogen: Human CTLA-4/human IgG heavy chain fusion protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/X63-Ag8.653 myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 20 μL of neat antibody to label 5x10e5 cells in 100 μL. Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 0.2 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute only prior to immediate use

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152 / CTLA4

Hintergrund: CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present within the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

Gen-ID: 1493

NCBI Accession: NP_001032720

UniProt: P16410

Pathways: Cancer Immune Checkpoints