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CTLA4 Antikörper

CTLA4 Reaktivität: Human FACS, Func, IHC (fro), EIA Wirt: Maus Monoclonal BNI3 unconjugated
Produktnummer ABIN118890
  • Target Alle CTLA4 Antikörper anzeigen
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reaktivität
    • 113
    • 73
    • 32
    • 4
    • 3
    Human
    Wirt
    • 70
    • 60
    • 23
    • 7
    • 1
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 98
    • 62
    • 3
    Monoklonal
    Konjugat
    • 77
    • 16
    • 13
    • 11
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTLA4 Antikörper ist unkonjugiert
    Applikation
    • 93
    • 64
    • 59
    • 32
    • 22
    • 17
    • 13
    • 12
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Spezifität
    Highly specific for CD152 (CTAL-4).
    Immunogen
    Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig)
    Klon
    BNI3
    Isotyp
    IgG2a
    Top Product
    Discover our top product CTLA4 Primärantikörper
  • Applikationshinweise
    Research studies by Microscopy or Flow cytometry, after in vitro activation of T cells with selected stimuli (Concanavalin A, or solid-phase fixed-CD3 + CD28 Mabs stimulation). Research studies on CTLA-4 expression on B cells and on CTLA-4 expression by Immunohistochemistry only on frozen tissue sections. Fluorescence microscopy or Flow cytometry: 2 μg/5x10e5 cells/test. Cytospin or immunohistochemistry on frozen tissue sections: Working concentration is 5-50 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with 1 mL of distilled water.
    Buffer
    PBS, pH 7.2, containing 1 mg/mL BSA as stabilizer without preservatives
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Andere Bezeichnung
    CD152 / CTLA4 (CTLA4 Produkte)
    Hintergrund
    The cytolytic T-lymphocyte-associated antigen 4 (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45 kDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5).Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    Gen-ID
    1493
    NCBI Accession
    NP_001032720
    UniProt
    P16410
    Pathways
    Cancer Immune Checkpoints
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