CD44 Antikörper

Produktnummer ABIN118695

Dieser Anti-CD44 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD44 in FACS, WB, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für CD44 Antikörper (ABIN118695)

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: VFF-9

Produktdetails anti-CD44 Antikörper

Aufreinigung: Purified

Immunogen: Human CD44v7.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Western Blot. Immunohistochemistry on frozen sections: 1/50. Immunohistochemistry on paraffin sections: 1/50, This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: CD44 is a receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post translational modification events.Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I

Gen-ID: 960

NCBI Accession: NP_000601

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling