CD35 Antikörper

Produktnummer ABIN118608

Produktdetails anti-CD35 Antikörper

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reaktivität: Human, Pavian, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD35 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Human acute monocytic leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Klon: E11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 10^6 cells or 100 μL whole blood. Immunohistochemistry on Frozen Section: 1-10 μg/mL. Immunohistochemistry on Paraffin Section: 1-10 μg/mL. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections, Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD35

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Andere Bezeichnung: CD35 / C3BR (CR1 Produkte)

Synonyme: C3BR antikoerper, C4BR antikoerper, CD35 antikoerper, KN antikoerper, C3DR antikoerper, CD21 antikoerper, Cr-1 antikoerper, Cr-2 antikoerper, Cr1 antikoerper, CR1-L antikoerper, CR2 antikoerper, CR1 antikoerper, complement C3b/C4b receptor 1 (Knops blood group) antikoerper, complement receptor 2 antikoerper, complement component (3d/Epstein Barr virus) receptor 2 antikoerper, complement receptor type 1 antikoerper, CR1 antikoerper, Cr2 antikoerper, CR2 antikoerper, LOC718120 antikoerper

Hintergrund: CD35 is a single chain cell surface glycoprotein which exists in four allotypic forms (A,B,C,D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement.Synonyms: C3b/C4b receptor, CR1, Complement receptor type 1

Gen-ID: 9606

UniProt: P17927

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity